by Wei Liu | Mar 26, 2021 | Blog
Parkinson Disease: a common neurodegenerative disorder Parkinson diseases (PD) is the second most common neurodegenerative disorder that usually has a late onset; it affects 1% of the population over age 60 and a total 4million people in the globe. The people with PD...
by Wei Liu | Mar 11, 2021 | Blog, Uncategorized
Bacteria and pathogen identification and methods Microbes or pathogens identification is common for both research (microbial community studies) and clinics (pathogen identification for infectious diseases). In clinical microbiology labs, fast and correct...
by Wei Liu | Feb 26, 2021 | Blog
SNPs and Human Diseases SNPs, single nucleotide polymorphism, is the simplest genetic variation and occurs in every 1000 bases in human genomic DNA. Among the 3.5 million SNPs, some lie in intergenic regions (non-coding regions that play regulatory roles) while others...
by Wei Liu | Sep 24, 2021 | Blog
Rolling circle amplification (RCA) Based on the natural rolling circle replication from bacterial plasmids, bacteriophage, and viruses, rolling circle amplification (RCA) technique was developed and widely used in molecular biology research applications including...
by Wei Liu | Nov 19, 2021 | Blog
Sanger Sequencing and NGS Sanger sequencing as a gold standard for DNA sequencing is still commonly used in clinical settings. However, there is a trend that many clinical tests are using NGS to replace Sanger sequencing. The practice leverages the throughput,...
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