by Wei Liu | Apr 5, 2021 | Blog
Sanger sequencing data files can be used to measure copy number proportions A couple of months ago, we read the overlapping peaks of both the wildtype and the BRAF V600E mutant traces in the electropherogram of Sanger sequencing from a clinical sample. We wanted to...
by Wei Liu | May 19, 2021 | Blog
Covid-19 and Variants of Concern Since its first occurrence in 2019, COVID-19 has been spreading globally infecting close to 165 million people and having killed more than 3.4 million people as of May19, 2021. The CDC has recommended self-protection measures such as...
by Wei Liu | Sep 17, 2021 | Blog
Importance of cleaning cycle sequencing reactions In the sanger sequencing workflow, cycle sequencing reaction is certainly the core and critical step because the reaction determines if the extension products are appropriately synthesized and labeled with great...
by Wei Liu | Oct 8, 2021 | Blog
A simple introduction of CRISPR Clustered Regularly Interspaced Short Palindromic Repeat or CRISPR as a part of bacterial defense system against bacteriophage is used as a dominating gene-editing tool to make changes in targeted DNA sequences. The most popular...
by Wei Liu | Jan 18, 2022 | Blog
Capillary array as a carrier for polymers, the separation media, is critical for peak separation in Sanger sequencing and fragment analysis. Each capillary array costs several thousands of dollars; taking good care of the capillary array goes a long way for saving...
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